Biopharmaceutics and Pharmacokinetic MCQs and Notes

G

Gopal Sharma • 28.64K Points
Instructor II

Q 21. Which of the following is not a category of 2 compartment model?

(A) Two compartment model with elimination from the central compartment

(B) Two compartment model with elimination from the peripheral compartment

(C) Two compartment model with elimination from only plasma and blood

(D) Two compartment model with elimination from both the compartments

P

Priyanka Tomar • 25.98K Points
Instructor II

Q 22. Which organ comprises the peripheral compartment in a two compartment model?

(A) Liver

(B) Lungs

(C) Kidneys

(D) Muscles

M

Mohini Yadav • 27.60K Points
Instructor II

Q 23. Which organs comprise the central compartment in a two compartment model?

(A) Muscles

(B) Skin

(C) Adipose

(D) Liver

R

Rakesh Kumar • 19.20K Points
Tutor I

Q 24. What is the equation to find out hepatic clearance?

(A) Plasma drug concentration/rate of elimination by the kidney

(B) Rate of elimination by kidney/plasma drug concentration

(C) 1 / rate of elimination by the kidney

(D) 1 / plasma drug concentration

S

Shiva Ram • 21.45K Points
Instructor III

Q 25. To have a plasma distribution value of 900 ml and plasma drug concentration to be 1.2 mg/ml what should be the amount of drug that should be given to the patient?

(A) 1080 ml

(B) 1080 g

(C) 1080 mg

(D) 1g/ml

R

Ranjeet • 25.13K Points
Instructor II

Q 26. The i.v. bolus dosage is 500mg and the plasma drug concentration is 0.8 mg/ml. What should be the volume of distribution?

(A) 625 mg/ml

(B) 625 l

(C) 625 ml

(D) 0.0016 mg/ml

R

Ram Sharma • 188.81K Points
Coach

Q 27. What is the equation to find out the apparent volume of distribution?

(A) Amount of drug in the body/plasma drug concentration

(B) Plasma drug concentration/amount of drug in the body

(C) 1 / plasma drug concentration

(D) 1 / Amount of drug in the body

R

Ram Sharma • 188.81K Points
Coach

Q 28. What is meant by elimination half-life?

(A) Time take for half of the amount of drug to get completely eliminated from only the organs

(B) Time take for half of the amount of drug to get completely eliminated from only blood

(C) Time take for half of the amount of drug to get completely eliminated from only plasma

(D) Time take for half of the amount of drug to get completely eliminated from the body as well as plasma

V

Vijay Sangwan • 19.12K Points
Tutor I

Q 29. In the equation log C = log Co – KEt/2.303, what does Co stand for _______

(A) Plasma drug concentration after 60 min of i.v. injection

(B) Plasma drug concentration after 15 min of i.v. injection

(C) Plasma drug concentration after 30 min of i.v. injection

(D) Plasma drug concentration immediately after i.v. injection.

V

Vinay • 19K Points
Tutor I

Q 30. How much time does an intravenously administered drug take to complete a complete circulation?

(A) 5-8 min

(B) 7-10 min

(C) 1-3 min

(D) 1 min

Biopharmaceutics and Pharmacokinetic

Q 21. Which of the following is not a category of 2 compartment model?

Q 22. Which organ comprises the peripheral compartment in a two compartment model?

Q 23. Which organs comprise the central compartment in a two compartment model?

Q 24. What is the equation to find out hepatic clearance?

Q 25. To have a plasma distribution value of 900 ml and plasma drug concentration to be 1.2 mg/ml what should be the amount of drug that should be given to the patient?

Q 26. The i.v. bolus dosage is 500mg and the plasma drug concentration is 0.8 mg/ml. What should be the volume of distribution?

Q 27. What is the equation to find out the apparent volume of distribution?

Q 28. What is meant by elimination half-life?

Q 29. In the equation log C = log Co – KEt/2.303, what does Co stand for _______

Q 30. How much time does an intravenously administered drug take to complete a complete circulation?

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