Q. Which organ is primarily responsible for detoxification and metabolism of drugs in the human body?
✅ Correct Answer: (B)
Liver
Explanation: The liver metabolizes drugs and detoxifies many substances via enzymes (e.g., cytochrome P450). Kidneys excrete waste and filter blood but do less metabolic detoxification. Spleen filters blood and recycles red cells, pancreas produces digestive enzymes and hormones — not primary detox organ.
Explanation by: Mr. Dubey
The liver metabolizes drugs and detoxifies many substances via enzymes (e.g., cytochrome P450). Kidneys excrete waste and filter blood but do less metabolic detoxification. Spleen filters blood and recycles red cells, pancreas produces digestive enzymes and hormones — not primary detox organ.