Q. Which one of the following statements is NOT true?

• (A) In competitive inhibition, substrate and inhibitor compete for the same active site of an enzyme
• (B) Addition of a large amount of substrate to an enzyme cannot overcome uncompetitive inhibition
• (C) A transition state analogue in enzyme catalyzed reaction increases the rate of product formation
• (D) In non-competitive inhibition, KM of an enzyme for its substrate remains constant as the concentration of the inhibitor increases