Hayflick limit of mammalian cells refers to which one of the following?

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Mr. Dubey

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📊 Cell Biotechnology

Q. Hayflick limit of mammalian cells refers to which one of the following?

(A) Cells in primary cell culture undergo senescence after 50-60 passages
(B) Primary cells cultured in vitro do not cross the limit of cell transformation
(C) Cell lines when cultured in vitro have a limit for their surface to volume ratio
(D) Malignant cell lines undergo senescence after 50-60 passages

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✅ Correct Answer: (A) Cells in primary cell culture undergo senescence after 50-60 passages

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