What is the primary purpose of neomycin in creating mice with knockouts in gene X?

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Mr. Dubey

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📊 Animal Biotechnology

Q. What is the primary purpose of neomycin in creating mice with knockouts in gene X?

(A) Neomycin selects for the survival of embryonic stem cells (ES) that have incorporated the mutant gene X anywhere in the genome
(B) Neomycin selects for the survival of ES cell that have incorporated the mutant gene in the place of the wild-type gene
(C) Neomycin prevents Candida infection during ES cell culture that does not have gene X
(D) Neomycin makes the gene X knock-out mice resistant to Candida infection

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✅ Correct Answer: (A) Neomycin selects for the survival of embryonic stem cells (ES) that have incorporated the mutant gene X anywhere in the genome

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