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Mr. Dubey • 100.64K Points
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Q. Which of the following statements regarding the supercoiling of duplex DNA is correct?

  • (A) DNA replication promotes positive supercoiling downstream from the replication fork
  • (B) DNA polymerase III can replicate positively supercoiled duplex DNA
  • (C) DNA topoisomerases unwind duplex DNA into single-stranded DNA chains
  • (D) DNA topoisomerases unwind positively supercoiled duplex DNA without cutting the phosphosugar backbone
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