Cells deficient in hypoxanthine guanine phosphoribosyl-transferase (HPRT) enzyme rely on

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📊 Animal Biotechnology

Q. Cells deficient in hypoxanthine guanine phosphoribosyl-transferase (HPRT) enzyme rely on

(A) Synthesis of purine deoxynucleotides by salvage pathway
(B) Synthesis of purine deoxynucleotides by de novo pathway
(C) Supply of hypoxanthine in the culture medium
(D) Supply of thymidine in the culture medium

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✅ Correct Answer: (B) Synthesis of purine deoxynucleotides by de novo pathway

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