Q. The genome-wide comparative mRNA expression profile between normal and cancer cells can be studied using the microarray technology. The basic approach of this technology is

  • (A) Hybridization of fluorescently labelled genomic DNA from human cells to normal and cancer cell cDNA immobilized onto two glass slides
  • (B) Hybridization of fluorescently labelled cDNAs from normaland cancer cells to a single glass slide containing immobilized clones of human genomic DNA
  • (C) Hybridization of fluorescently labelled cDNAs from normal and cancer cells to a single glass slide containing immobilized clones of human cDNAs
  • (D) Hybridization of fluorescently labelled genomic DNA from normal and cancer cells to immobilized human cDNAs on a single glass slide
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βœ… Correct Answer: (C) Hybridization of fluorescently labelled cDNAs from normal and cancer cells to a single glass slide containing immobilized clones of human cDNAs

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