Q. The first level of regulation of gene expression in eukaryotes is

  • (A) Transcription
  • (B) DNA methylation and chromatin structure
  • (C) RNA processing
  • (D) Post transcriptional modification
πŸ’¬ Discuss
βœ… Correct Answer: (B) DNA methylation and chromatin structure

Q. Enzyme which digest nucleic acid by hydrolyzing phosphodiester bonds are called as

  • (A) Nucleases
  • (B) Deoxyribonucleases (if substrate is DNA)
  • (C) Ribonucleases (if substrate is RNA)
  • (D) All of the above
πŸ’¬ Discuss
βœ… Correct Answer: (D) All of the above

Q. The size of the maximum DNA insert that can be cloned in a YAC

  • (A) < 300 kb
  • (B) 100 - 300 kb
  • (C) 70 - 100 kb
  • (D) 200 - 2000 kb
πŸ’¬ Discuss
βœ… Correct Answer: (D) 200 - 2000 kb

Q. In a double stranded molecule of DNA, the ratio of purines : pyrimidines is

  • (A) Variable
  • (B) Determined by the base sequence in RNA
  • (C) Genetically determined
  • (D) Always 1 : 1
πŸ’¬ Discuss
βœ… Correct Answer: (D) Always 1 : 1

Q. The smallest plant genome identified

  • (A) Chlorella
  • (B) Oryza sativa
  • (C) Arabidopsis
  • (D) Ground nut
πŸ’¬ Discuss
βœ… Correct Answer: (C) Arabidopsis

Q. Which one of the following amino acid has crucial role in the variability of protein structure?

  • (A) Glycine
  • (B) Cysteine
  • (C) Aspartic acid
  • (D) Glutamic acid
πŸ’¬ Discuss
βœ… Correct Answer: (A) Glycine

Q. Transcription is the process of

  • (A) Synthesizing a DNA molecule from RNA template
  • (B) Using DNA strand as a template to synthesize a complementary RNA molecule
  • (C) Using DNA strand as template to synthesize identical RNA molecule
  • (D) Synthesizing a protein using information carried in the nucleotide sequence of a messenger RNA
πŸ’¬ Discuss
βœ… Correct Answer: (B) Using DNA strand as a template to synthesize a complementary RNA molecule

Q. The ability of proteins to absorb ultraviolet light is predominantly due to the presence of

  • (A) Disulphide bond
  • (B) Hydrophobic amino acids
  • (C) Tryptophan
  • (D) Hydrophilic amino acids
πŸ’¬ Discuss
βœ… Correct Answer: (C) Tryptophan

Q. Which of the following statement about the ribosome complex is correct?

  • (A) Small subunit binds an mRNA and large subunit joint with the mRNA/small subunit complex to form a complete ribosome
  • (B) The large ribosomal subunit has a P site (peptidyl site) that holds the growing polypeptide chain and an A site (aminoacyl site) that binds the next amino acid to be added to the growing polypeptide chain
  • (C) The additon of new amino acid in the A site to the growing polypeptide chain is catalyzed by one of the enzymes that form the large ribosomal subunit
  • (D) All of the above
πŸ’¬ Discuss
βœ… Correct Answer: (D) All of the above

Q. DNA polymerase involved in general DNA replication in eukaryotes is

  • (A) α
  • (B) β
  • (C) A and B both
  • (D) γ
πŸ’¬ Discuss
βœ… Correct Answer: (C) A and B both

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