Q. Which one of the following is an ABC transporter?

  • (A) Multidrug resistance protein
  • (B) Acetylcholine receptor
  • (C) Bacteriorhodopsin
  • (D) ATP synthase
πŸ’¬ Discuss
βœ… Correct Answer: (A) Multidrug resistance protein

Q. Natural proteins are composed primarily of 20 α-amino acids. Which one of the following statements is true for any of these amino acids in a solution of pH 1.5?

  • (A) Only the amino group is ionized
  • (B) Only the carboxylic acid group is ionized
  • (C) Both amino and carboxylic acid groups are ionized
  • (D) Both amino and carboxylic add groups are neutral
πŸ’¬ Discuss
βœ… Correct Answer: (A) Only the amino group is ionized

Q. Which one of the following statements is NOT true?

  • (A) In competitive inhibition, substrate and inhibitor compete for the same active site of an enzyme
  • (B) Addition of a large amount of substrate to an enzyme cannot overcome uncompetitive inhibition
  • (C) A transition state analogue in enzyme catalyzed reaction increases the rate of product formation
  • (D) In non-competitive inhibition, KM of an enzyme for its substrate remains constant as the concentration of the inhibitor increases
πŸ’¬ Discuss
βœ… Correct Answer: (C) A transition state analogue in enzyme catalyzed reaction increases the rate of product formation

Q. Levinthal's paradox is related to

  • (A) Protein secretion
  • (B) Protein degradation
  • (C) Protein folding
  • (D) Protein trafficking
πŸ’¬ Discuss
βœ… Correct Answer: (C) Protein folding

Q. An enzymatic reaction exhibits Michaelis-Menten kinetics. For this reaction, on doubling the concentration of enzyme while maintaining [S] >> [E0],

  • (A) Both KM and Vmax will remain the same
  • (B) KM will remain the same but Vmax will increase
  • (C) KM will increase but Vmax will remain the same
  • (D) Both KM and Vmax will increase
πŸ’¬ Discuss
βœ… Correct Answer: (B) KM will remain the same but Vmax will increase

Q. In general, which one of the following statements is NOT CORRECT?

  • (A) Hydrogen bonds result from electrostatic interactions
  • (B) Hydrogen bonds contribute to the folding energy of proteins
  • (C) Hydrogen bonds are weaker than van der Waals interactions
  • (D) Hydrogen bonds are directional
πŸ’¬ Discuss
βœ… Correct Answer: (C) Hydrogen bonds are weaker than van der Waals interactions

Q. Which one of the following statements is CORRECT for enzyme catalyzed reactions? ( ΔG is Gibbs free energy change, Keq is equilibrium constant)

  • (A) Enzymes affect ΔG, but not Keq
  • (B) Enzymes affect Keq, but not ΔG
  • (C) Enzymes affect ΔG and Keq
  • (D) Enzymes do not affect ΔG or Keq
πŸ’¬ Discuss
βœ… Correct Answer: (A) Enzymes affect ΔG, but not Keq

Q. ATP biosynthesis takes place utilizing the H+ gradient in mitochondria and chloroplasts. Identify the correct sites of H+ gradient formation.

  • (A) Across the outer membrane of mitochondria and across the inner membrane of chloroplast
  • (B) Across the inner membrane of mitochondria and across the thylakoid membrane of chloroplast
  • (C) Within the matrix of mitochondria and across the inner membrane of chloroplast
  • (D) Within the matrix of mitochondria and within the stroma of chloroplast
πŸ’¬ Discuss
βœ… Correct Answer: (B) Across the inner membrane of mitochondria and across the thylakoid membrane of chloroplast

Q. An enzyme catalyzes a reaction by

  • (A) Decreasing the energy of the substrate
  • (B) Decreasing the activation energy of the reaction
  • (C) Decreasing product stability
  • (D) Increasing the activation barrier of the reaction
πŸ’¬ Discuss
βœ… Correct Answer: (B) Decreasing the activation energy of the reaction

Q. Which one of the following need NOT be conserved in a biochemical reaction?

  • (A) Total mass
  • (B) Total moles
  • (C) Number of atoms of each element
  • (D) Total energy
πŸ’¬ Discuss
βœ… Correct Answer: (B) Total moles

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