The most important reason for the thiazides being only moderately efficacious diuretics is: | Faculties

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Rakesh Kumar

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📊 Pharmaceutical Chemistry - Medicinal Chemistry 4

Q. The most important reason for the thiazides being only moderately efficacious diuretics is:

(A) About 9/10th of glomerular filtrate is reabsorbed proximal to their site of action
(B) Compensatory increase in reabsorption at sites not affected by these drugs
(C) They decrease glomerular filtration
(D) They have relatively flat dose response curve

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✅ Correct Answer: (A) About 9/10th of glomerular filtrate is reabsorbed proximal to their site of action

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