Identify the reaction: When thiophene react with dimethyl formamide in the presence of POCl3, it will produce thiophene – 2 – carboxaldehyde. | Faculties

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📊 Pharmaceutical Organic Chemistry 3

Q. Identify the reaction: When thiophene react with dimethyl formamide in the presence of POCl3, it will produce thiophene – 2 – carboxaldehyde.

(A) Kolbe reaction
(B) Canizzaro reaction
(C) Gattermann Koch reaction
(D) Vilsmeir – Hoack reaction

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✅ Correct Answer: (D) Vilsmeir – Hoack reaction

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