Q. What is the major end product of oxidation of aromatic carbon atoms?
✅ Correct Answer: (A)
Arenols
Medicinal Chemistry 1 MCQs and Notes
Q. Which of the following reactions is not a Phase I metabolic transformation?
✅ Correct Answer: (B)
Conjugation to alcohols
Q. Which of the following enzymes is not involved in catalyzing Phase I metabolic reaction?
✅ Correct Answer: (C)
Glucuronyl transferase
Q. Which of the following is not a characteristic of the moieties that are transferred to the substrate in phase II reactions?
✅ Correct Answer: (D)
Strong nonpolar groups are attached
Q. Which of the following statements is the closest description of Phase II metabolism?
✅ Correct Answer: (A)
Reactions which add a polar molecule to a functional group already present on a drug or one of its metabolites.
Q. Which of the following statements is the closest description of Phase I metabolism?
✅ Correct Answer: (C)
Reactions which add a polar functional group to a drug.
Q. Following are the Phase I reactions except ____________
✅ Correct Answer: (D)
Sulphide reactions
Q. The phase II reactions are detoxification pathways.
✅ Correct Answer: (A)
True
Q. The phase I reactions are detoxification pathways.
✅ Correct Answer: (A)
True
Q. Phase 1 reactions are also known as a synthetic reaction.
✅ Correct Answer: (A)
True