Q. UDPGA means....
✅ Correct Answer: (B)
Uridine diphospho -a- D glucuronic acid
Medicinal Chemistry 1 MCQs and Notes
Q. __________reaction is most common in drugs having ester or amide functional groups
✅ Correct Answer: (C)
Hydrolysis
Q. Diazepam gets metabolised into Hydroxydiazepam is example of
✅ Correct Answer: (B)
Oxidation at the carbon alpha to carbonyl and imino group
Q. Higher will be the diffusion of the drug across the membrane if
✅ Correct Answer: (A)
Higher value of partition-coefficient
Q. Solubility of a drug in polar solvents and Non-polar solvents depends upon
✅ Correct Answer: (D)
All of above
Q. Alkenes and aromatic groups can be metabolised to diols. Which enzymes are involved?
✅ Correct Answer: (C)
both of the above
Q. Which of the following groups is least susceptible to cytochrome P450 enzymes?
✅ Correct Answer: (D)
Quaternary carbon atoms
Q. Which enzyme is important in the Phase II reactions?
✅ Correct Answer: (C)
Transferase
Q. What does the hydrolysis of Aspirin yield us with?
✅ Correct Answer: (B)
Salicylic acid and CH3COOH
Q. Which of the following is not a common N containing functional groups which undergo reduction reactions?
✅ Correct Answer: (D)
Nitrite compounds