πŸ“Š Physical Pharmaceutics 2
Q. The storage directions on a parenteral solution specify ‘store in a cool place’. This may be stored in:
  • (A) an air-conditioned area at 10°C
  • (B) a refrigerator at 15°C
  • (C) a place whose temperature is set at 5°C
  • (D) room temperature, at 25°C
πŸ’¬ Discuss
βœ… Correct Answer: (B) a refrigerator at 15°C
πŸ“Š Physical Pharmaceutics 2
Q. During storage, crystal growth is observed in a suspension due to:
  • (A) absorption of water
  • (B) fluctuations in the ambient temperatures
  • (C) presence of suspending agent
  • (D) volatilization of solids
πŸ’¬ Discuss
βœ… Correct Answer: (B) fluctuations in the ambient temperatures
πŸ“Š Physical Pharmaceutics 2
Q. Which one of these methods is the MOST effective in preventing the rate of hydrolysis?
  • (A) buffer
  • (B) complexation
  • (C) removal of water
  • (D) suppression of solubility
πŸ’¬ Discuss
βœ… Correct Answer: (C) removal of water
πŸ“Š Physical Pharmaceutics 2
Q. For the validity of accelerated stability studies of solution dosage form, the energy of activation should be in the range of (in units of kcal/mole).
  • (A) 0 to 10
  • (B) 11 to 30
  • (C) 31 to 50
  • (D) 51 to 70
πŸ’¬ Discuss
βœ… Correct Answer: (B) 11 to 30
πŸ“Š Physical Pharmaceutics 2
Q. Which one of the following is primarily NOT a chemical decomposition?
  • (A) isomerisation
  • (B) hydrolysis
  • (C) oxidation
  • (D) volatilization
πŸ’¬ Discuss
βœ… Correct Answer: (D) volatilization
πŸ“Š Physical Pharmaceutics 2
Q. Aspirin undergoes decomposition in a formulation. It can be prevented by:
  • (A) adding a chelating agent
  • (B) adding an antioxidant
  • (C) protecting it from light
  • (D) suppressing its solubility
πŸ’¬ Discuss
βœ… Correct Answer: (D) suppressing its solubility
πŸ“Š Physical Pharmaceutics 2
Q. Which of the following reactions is observed in the degradation of ampicillin?
  • (A) decarboxylation
  • (B) hydrolysis
  • (C) oxidation
  • (D) recimization
πŸ’¬ Discuss
βœ… Correct Answer: (B) hydrolysis
πŸ“Š Physical Pharmaceutics 2
Q. On a product, the label states ‘protect from light’. What type of decomposition does the product undergo?
  • (A) carboxylation
  • (B) decarboxylation
  • (C) hydrolysis
  • (D) oxidation
πŸ’¬ Discuss
βœ… Correct Answer: (D) oxidation
πŸ“Š Physical Pharmaceutics 2
Q. In injections, procaine undergoes the degradation reactions in the following sequence:
  • (A) decarboxylation and hydrolysis
  • (B) hydrolysis and decarboxylation
  • (C) hydrolysis, decarboxylation and oxidation
  • (D) oxidation, decarboxylation and hydrolysis
πŸ’¬ Discuss
βœ… Correct Answer: (B) hydrolysis and decarboxylation
πŸ“Š Physical Pharmaceutics 2
Q. During autoclaving of dextrose solution, a straw colour is observed. It is due to the presence of a substance called:
  • (A) furfural
  • (B) 5-hydroxymethylfurfural
  • (C) 5-hydroxyfurfural
  • (D) 5-methylfurfural
πŸ’¬ Discuss
βœ… Correct Answer: (B) 5-hydroxymethylfurfural