Q. For their efficient translation, eubacterial mRNAs possess a Shine-Dalgarno sequence for its recognition by an anti-Shine-Dalgarno sequence (ASD) in the ribosomes. The correct statement is

  • (A) ASD is present in 5S rRNA
  • (B) ASD is present in 23S rRNA
  • (C) ASD is present in 16S rRNA
  • (D) ASD is formed by the interaction of the 16S rRNA with the 23S rRNA upon docking of the 50S subunit on the 30S subunit of the ribosomes
πŸ’¬ Discuss
βœ… Correct Answer: (C) ASD is present in 16S rRNA

Q. Peptidyl transferase activity resides in

  • (A) 16S rRNA
  • (B) 23S rRNA
  • (C) 5S rRNA
  • (D) 28S rRNA
πŸ’¬ Discuss
βœ… Correct Answer: (B) 23S rRNA

Q. DNA helicases catalyze the reaction

  • (A) DNA supercoiling
  • (B) DNA unwinding
  • (C) Cleavage of DNA helix
  • (D) Interconversion of DNA topoisomers
πŸ’¬ Discuss
βœ… Correct Answer: (B) DNA unwinding

Q. The formation of peptide cross links between adjacent glycan chains in cell wall synthesis is called

  • (A) Transglycosylation
  • (B) Autoglycosylation
  • (C) Autopeptidation
  • (D) Transpeptidation
πŸ’¬ Discuss
βœ… Correct Answer: (D) Transpeptidation

Q. In a relatively large but finite and closed population of sexually reproducing diploid organisms, the frequency of homozygous genotype PP changes from 0.40 to 0.50 and that of pp changes from 0.40 to 0.41 in a span of 10 generations. Which of the following is the most likely cause for the above change in frequency of the PP genotype?

  • (A) Non-random mating
  • (B) Random genetic drift
  • (C) Selection
  • (D) Combination of non-random mating and random genetic drift
πŸ’¬ Discuss
βœ… Correct Answer: (C) Selection

Q. In nature, the horizontal gene transfer across bacteria is mediated by

  • (A) Gene cloning followed by transformation
  • (B) Conjugation and transformation
  • (C) Conjugation only
  • (D) Transformation only
πŸ’¬ Discuss
βœ… Correct Answer: (B) Conjugation and transformation

Q. Which one of the following covalent linkages exists between 7-Methyl guanosine (m7G) and mRNAs?

  • (A) 2' - 3' triphosphate
  • (B) 3' - 5' triphosphate
  • (C) 5' - 5' triphosphate
  • (D) 2' - 5' triphosphate
πŸ’¬ Discuss
βœ… Correct Answer: (C) 5' - 5' triphosphate

Q. siRNA(s) interfere at

  • (A) Transcriptional level
  • (B) Post-transcriptional level
  • (C) DNA replication level
  • (D) Translational level
πŸ’¬ Discuss
βœ… Correct Answer: (B) Post-transcriptional level

Q. Hypophosphatemia is manifested by an X-linked dominant allele. What proportion of the offspring from a normal male and an affected heterozygous female will manifest the disease?

  • (A) $${1 \over 2}$$ sons and $${1 \over 2}$$ daughters
  • (B) All daughters and no sons
  • (C) All sons and no daughters
  • (D) $${1 \over 4}$$ daughters and $${1 \over 4}$$ sons
πŸ’¬ Discuss
βœ… Correct Answer: (A) $${1 \over 2}$$ sons and $${1 \over 2}$$ daughters

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