Molecular Biology and Genetics MCQs | Page - 1

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Mr. Dubey • 52.33K Points
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Q. Based on their function, find the odd one out

(A) miRNA
(B) siRNA
(C) shRNA
(D) snRNA
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Mr. Dubey • 52.33K Points
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Q. For their efficient translation, eubacterial mRNAs possess a Shine-Dalgarno sequence for its recognition by an anti-Shine-Dalgarno sequence (ASD) in the ribosomes. The correct statement is

(A) ASD is present in 5S rRNA
(B) ASD is present in 23S rRNA
(C) ASD is present in 16S rRNA
(D) ASD is formed by the interaction of the 16S rRNA with the 23S rRNA upon docking of the 50S subunit on the 30S subunit of the ribosomes
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Mr. Dubey • 52.33K Points
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Q. Peptidyl transferase activity resides in

(A) 16S rRNA
(B) 23S rRNA
(C) 5S rRNA
(D) 28S rRNA
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Mr. Dubey • 52.33K Points
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Q. DNA helicases catalyze the reaction

(A) DNA supercoiling
(B) DNA unwinding
(C) Cleavage of DNA helix
(D) Interconversion of DNA topoisomers
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Mr. Dubey • 52.33K Points
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Q. The formation of peptide cross links between adjacent glycan chains in cell wall synthesis is called

(A) Transglycosylation
(B) Autoglycosylation
(C) Autopeptidation
(D) Transpeptidation
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Mr. Dubey • 52.33K Points
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Q. In a relatively large but finite and closed population of sexually reproducing diploid organisms, the frequency of homozygous genotype PP changes from 0.40 to 0.50 and that of pp changes from 0.40 to 0.41 in a span of 10 generations. Which of the following is the most likely cause for the above change in frequency of the PP genotype?

(A) Non-random mating
(B) Random genetic drift
(C) Selection
(D) Combination of non-random mating and random genetic drift
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Mr. Dubey • 52.33K Points
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Q. In nature, the horizontal gene transfer across bacteria is mediated by

(A) Gene cloning followed by transformation
(B) Conjugation and transformation
(C) Conjugation only
(D) Transformation only
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Mr. Dubey • 52.33K Points
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Q. Which one of the following covalent linkages exists between 7-Methyl guanosine (m7G) and mRNAs?

(A) 2' - 3' triphosphate
(B) 3' - 5' triphosphate
(C) 5' - 5' triphosphate
(D) 2' - 5' triphosphate
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Mr. Dubey • 52.33K Points
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Q. siRNA(s) interfere at

(A) Transcriptional level
(B) Post-transcriptional level
(C) DNA replication level
(D) Translational level
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Mr. Dubey • 52.33K Points
Coach

Q. Hypophosphatemia is manifested by an X-linked dominant allele. What proportion of the offspring from a normal male and an affected heterozygous female will manifest the disease?

(A) $${1 \over 2}$$ sons and $${1 \over 2}$$ daughters
(B) All daughters and no sons
(C) All sons and no daughters
(D) $${1 \over 4}$$ daughters and $${1 \over 4}$$ sons
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