Q. Reverse genetics means

  • (A) Finding the function of an ORF
  • (B) Finding the gene responsible for a trait
  • (C) RNA dependent DNA synthesis
  • (D) Convening somatic cell to a germ cell
πŸ’¬ Discuss
βœ… Correct Answer: (A) Finding the function of an ORF

Q. The cellular process which utilizes RNA-induced silencing complex to block gene expression is

  • (A) RNA editing
  • (B) RNA interference
  • (C) RNA polyadenylation
  • (D) RNA splicing
πŸ’¬ Discuss
βœ… Correct Answer: (B) RNA interference

Q. In a genetic cross between the genotypes WWXX and wwxx, the following phenotypic distributions were observed among the F2 progeny: WX, 562; wx, 158; Wx, 38; and wX, 42. Likewise, a cross between XXYY and xxyy yielded the following results: XY, 675; xy, 175; Xy, 72; and xY, 78. Similarly, a cross between WWYY and wwyy yielded: WY, 292; wy, 88; Wy, 12; and wY, 8. In all the genotypes, capital letters denote the dominant allele. Assume that the F1 progeny were self-fertilized in all three crosses. Also, double cross-over does not occur in this species. Which of the following is correct?

  • (A) Relative position: W-X-Y Distances: W-X = 5 map units, X-Y = 17 map units
  • (B) Relative position: X-Y-W Distances: X-Y = 15 map units, Y-W = 11 map units
  • (C) Relative position: Y-W-X Distances: Y-W = 5 map units, W-X = 11 map units
  • (D) Relative position: X-W-Y Distances: X-W = 5 map units, W-Y = 10 map units
πŸ’¬ Discuss
βœ… Correct Answer: (C) Relative position: Y-W-X Distances: Y-W = 5 map units, W-X = 11 map units

Q. The major groove of DNA is lined by

  • (A) N3 of purine and N1 of pyrimidine
  • (B) N7 of purine and O2 of pyrimidine
  • (C) N7 of purine and C4 of pyrimidine
  • (D) None of the above
πŸ’¬ Discuss
βœ… Correct Answer: (C) N7 of purine and C4 of pyrimidine

Q. An example for template independent DNA polymerase is

  • (A) DNA Polymerase I
  • (B) RNA polymerase
  • (C) Terminal deoxynucleotidyl transferase
  • (D) DNA polymerase III
πŸ’¬ Discuss
βœ… Correct Answer: (C) Terminal deoxynucleotidyl transferase

Q. Synteny refers to

  • (A) Gene duplication from a common ancestor
  • (B) A tree representation of related sequences
  • (C) The extent of similarity between two sequences
  • (D) Local conservation of gene order
πŸ’¬ Discuss
βœ… Correct Answer: (D) Local conservation of gene order

Q. If a segment of a sense strand of DNA is 5'-ATGGACCAGA-3', then the resulting RNA sequence after transcription is

  • (A) 5'-AGACCAGGTA-3'
  • (B) 5'-UCUGGUCCAU-3'
  • (C) 5'-UACCUGGUCU-3'
  • (D) 5'-AUGGACCAGA-3'
πŸ’¬ Discuss
βœ… Correct Answer: (D) 5'-AUGGACCAGA-3'

Q. Which of the following statements with respect to the orientation of the nitrogenous bases to the pentose sugars, and the puckering of the sugar, is correct?

  • (A) Anti, and 2'-endo in A form DNA
  • (B) Anti, and 2'-endo in B form DNA
  • (C) Syn, and 3'-endo in A form DNA
  • (D) Syn, and 3'-endo in B form DNA
πŸ’¬ Discuss
βœ… Correct Answer: (B) Anti, and 2'-endo in B form DNA

Q. Of the two diploid species, species I has 36 chromosomes and species II has 28 chromosomes. How many chromosomes would be found in an allotriploid individual?

  • (A) 42 or 54
  • (B) 46 or 50
  • (C) 74 or 86
  • (D) 84 or 108
πŸ’¬ Discuss
βœ… Correct Answer: (B) 46 or 50

Q. Ames test is used to determine

  • (A) The mutagenicity of a chemical
  • (B) Carcinogenicity of a chemical
  • (C) Both mutagenicity and carcinogenicity of a chemical
  • (D) Toxicity of a chemical
πŸ’¬ Discuss
βœ… Correct Answer: (C) Both mutagenicity and carcinogenicity of a chemical

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