Q. Caspases are involved in the process of

  • (A) DNA replication
  • (B) Mutation and recombination
  • (C) Antibody synthesis
  • (D) Apoptosis
πŸ’¬ Discuss
βœ… Correct Answer: (D) Apoptosis

Q. During transcription,

  • (A) DNA gyrase introduces negative supercoils and DNA topoisomerase I removes negative supercoils
  • (B) DNA topoisomerase I introduces negative supercoils and DNA gyrase removes negative supercoils
  • (C) Both DNA gyrase and DNA topoisomearse I introduce negative supercoils
  • (D) Both DNA gyrase and DNA topoisomearse I remove negative supercoils
πŸ’¬ Discuss
βœ… Correct Answer: (C) Both DNA gyrase and DNA topoisomearse I introduce negative supercoils

Q. What will be the binding status of regulatory proteins in lac operon when concentrations of both lactose and glucose are very low in the culture medium?

  • (A) Only the repressor remains bound to the operator
  • (B) Only the cyclic AMP-Catabolic Activator Protein (cAMP-CAP) complex remains bound to the CAP binding site
  • (C) Neither the repressor nor cAMP-CAP complex remain bound to their respective binding sites
  • (D) Both the repressor and cAMP-CAP complex remain bound to their respective binding sites
πŸ’¬ Discuss
βœ… Correct Answer: (D) Both the repressor and cAMP-CAP complex remain bound to their respective binding sites

Q. The 5' ends of the mature forms of the prokaryotic mRNAs and tRNAs are

  • (A) A triphosphate group in mRNAs and a monophosphate group in tRNAs
  • (B) Triphosphate groups in both mRNAs and tRNAs
  • (C) Monophosphate groups in both mRNAs and tRNAs
  • (D) A monophosphate group in mRNAs and a triphosphate group in tRNAs
πŸ’¬ Discuss
βœ… Correct Answer: (A) A triphosphate group in mRNAs and a monophosphate group in tRNAs

Q. Nuclease-hypersensitive sites in the chromosomes are sites that appear to be

  • (A) H2 and H4 histone free
  • (B) H1 and H2 histone free
  • (C) H3 and H4 histone free
  • (D) Nucleosome free
πŸ’¬ Discuss
βœ… Correct Answer: (D) Nucleosome free

Q. How many different protein sequences of 100 residues can be generated using 20 standard amino acids?

  • (A) 10020
  • (B) 100 × 20
  • (C) 20100
  • (D) 100! × 20!
πŸ’¬ Discuss
βœ… Correct Answer: (C) 20100

Q. The G + C content of bacteriophage M13 double stranded DNA is 68%. What would you expect the G + C content of its mRNA?

  • (A) About 68%
  • (B) About 34%
  • (C) About 32%
  • (D) About 86%
πŸ’¬ Discuss
βœ… Correct Answer: (A) About 68%

Q. Efficient expression of a heterologous protein product is influenced by

  • (A) Transcriptional efficiency
  • (B) Copy number of the plasmid
  • (C) Codon bias
  • (D) All of the above
πŸ’¬ Discuss
βœ… Correct Answer: (D) All of the above

Q. The 4-amino or 4-keto group of pyrimidine bases is located in the

  • (A) Major groove of the double stranded DNA
  • (B) Minor groove of the double stranded DNA
  • (C) Minor groove of the B form DNA but not the A form DNA
  • (D) Major groove of the B form DNA but not the A form DNA
πŸ’¬ Discuss
βœ… Correct Answer: (A) Major groove of the double stranded DNA

Q. RNA is very much susceptible to hydrolysis in alkali because

  • (A) It contains uracil residues in its structure
  • (B) its 2'-OH group participate in intramolecular cleavage of phosphodiester backbone
  • (C) Cleavage occurs in the glycosylic bonds of purine bases
  • (D) Cleavage occurs in the glycosylic bonds of pyrimidine bases
πŸ’¬ Discuss
βœ… Correct Answer: (B) its 2'-OH group participate in intramolecular cleavage of phosphodiester backbone

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