Biopharmaceutics and Pharmacokinetic MCQs and Notes

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📊 Biopharmaceutics and Pharmacokinetic
Q. What reasons make tissue-drug binding important for drug distribution?
  • (A) Increases the volume of distribution of drugs and results in localization of drug at a specific site
  • (B) Increases the volume of distribution of drugs
  • (C) Results in localization of drugs at a tissue specific site
  • (D) Increases in absorption from the tissue due to concentration increasing
💬 Discuss
✅ Correct Answer: (A) Increases the volume of distribution of drugs and results in localization of drug at a specific site
📊 Biopharmaceutics and Pharmacokinetic
Q. In meningitis and encephalitis polar antibiotics gain access to BBB which don’t happen to a healthy person.
  • (A) True
  • (B) False
  • (C) none
  • (D) all
💬 Discuss
✅ Correct Answer: (A) True
📊 Biopharmaceutics and Pharmacokinetic
Q. The extent to which a drug is distributed is a tissue depends upon ___________ and _____________
  • (A) The concentration of a drug, tissue/blood partition coefficient of drug
  • (B) Tissue volume, tissue/blood partition coefficient of drug
  • (C) Tissue surface area, tissue/blood partition coefficient of drug
  • (D) Blood density upon the tissue, tissue/blood partition coefficient of drug
💬 Discuss
✅ Correct Answer: (B) Tissue volume, tissue/blood partition coefficient of drug
📊 Biopharmaceutics and Pharmacokinetic
Q. What is the consequence of diet high in fats?
  • (A) The patient can’t be given with acidic drugs
  • (B) The patient can’t be given with basic drugs
  • (C) The basic drugs will aggregate and become poisonous for him
  • (D) The high fatty acid level affect the binding of acidic drugs
💬 Discuss
✅ Correct Answer: (D) The high fatty acid level affect the binding of acidic drugs
📊 Biopharmaceutics and Pharmacokinetic
Q. What happens when an obese person is given with a lipophilic drug?
  • (A) Drug aggregation will begin
  • (B) He cannot absorb lipophilic drugs
  • (C) High adipose tissue take up most of the lipophilic drug
  • (D) A large amount of drug is needed as the person’s weight is more
💬 Discuss
✅ Correct Answer: (C) High adipose tissue take up most of the lipophilic drug
📊 Biopharmaceutics and Pharmacokinetic
Q. During pregnancy, drug distribution is more. Which of the following sentences describe the given fact better?
  • (A) The baby needs more drug
  • (B) The mother needs more drug due to high metabolism
  • (C) The surface area increases in the mother’s body due to the presence of uterus, placenta, and foetus. Thus more area for distribution of drugs
  • (D) The growth of the uterus, placenta, and foetus increases the volume thus increasing distribution. And even the baby forms a separate compartment for a drug to get distributed
💬 Discuss
✅ Correct Answer: (D) The growth of the uterus, placenta, and foetus increases the volume thus increasing distribution. And even the baby forms a separate compartment for a drug to get distributed

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