Q. Who has poorly developed BBB?
✅ Correct Answer: (A)
Infants
Biopharmaceutics and Pharmacokinetic MCQs and Notes
Q. Who has higher fat content?
✅ Correct Answer: (C)
Infants and elders
Q. Who has more intracellular and extracellular water more in their body?
✅ Correct Answer: (C)
Infants
Q. What is the perfusion rate?
✅ Correct Answer: (C)
The volume of blood that flows per unit time per unit volume of tissue
Q. What is the function of the blood-testis barrier?
✅ Correct Answer: (D)
Restricts the passage of drugs to spermatocytes and spermatids
Q. Which drugs can easily pass the Placental barrier?
✅ Correct Answer: (C)
Drugs having a molecular weight less than 1000 Dalton and moderate to high lipid solubility, analgesics, and antibiotics
Q. Which one of these is not an approach to make the drug cross the blood-brain barrier?
✅ Correct Answer: (C)
Use of highly lipophilic drug only
Q. Why dopamine cannot be administered for the disease Parkinsonism?
✅ Correct Answer: (C)
Cannot cross the blood-brain barrier
Q. What is the name of the specialized cells that support the blood-brain barrier tissue?
✅ Correct Answer: (A)
Astrocytes
Q. Which cell make up the blood-brain barrier?
✅ Correct Answer: (D)
Endothelial cells