Q. What could be the reason that irrespective of pH any drug gets absorbed mostly from the intestine?
✅ Correct Answer: (C)
Large surface area and long residence time
Biopharmaceutics and Pharmacokinetic MCQs and Notes
Q. Acidic drugs are best absorbed through the stomach and basic drugs are best absorbed through the intestine.
✅ Correct Answer: (A)
True
Q. What helps the ionized drug molecules to pass through the cell membrane passively?
✅ Correct Answer: (C)
Large lipophilic group
Q. According to the pH-partition theory which form of the drug gets absorbed mostly?
✅ Correct Answer: (D)
Unionised
Q. A microclimate pH, different from the luminal pH exists at the membrane surface.
✅ Correct Answer: (A)
True
Q. Which one of these options is not one of the limitations of pH-partition theory?
✅ Correct Answer: (D)
Dissolution rate
Q. Heroin with pKa 7.8 will be in which form in intestinal pH?
✅ Correct Answer: (B)
Unionized form mostly
Q. All drugs which are weak acids or acidic in nature will be in a unionized form in the plasma.
✅ Correct Answer: (B)
False
Q. Nitrazepam a weak base, will be in which form in the stomach?
✅ Correct Answer: (A)
Ionized form mostly
Q. Ibuprofen a weak acid, in the stomach will be present in which of the given form?
✅ Correct Answer: (B)
Non-ionized form mostly