Q. What should be the range of oil/water partition coefficient of any drug?
✅ Correct Answer: (A)
1-2
Biopharmaceutics and Pharmacokinetic MCQs and Notes
Q. Example of a drug which has PKa > 11 is ________
✅ Correct Answer: (D)
Mecamylamine
Q. Which one of these is not an example of a basic drug with pKa range 5-11?
✅ Correct Answer: (A)
Cromolyn
Q. Which one of these is an example of a strong acid drug?
✅ Correct Answer: (C)
Cromolyn
Q. Acids in the pKa range 2.5-7.5 are greatly affected by changes in pH making their absorption pH dependent.
✅ Correct Answer: (A)
True
Q. What is the pH range of the intestine?
✅ Correct Answer: (D)
5-8
Q. What is the pH range of the stomach?
✅ Correct Answer: (C)
1-3
Q. Which of the following equations correct for Henderson-Hasselbach equation for weak bases?
✅ Correct Answer: (D)
PH = pKa + log (Unionized drug concentration /Ionized drug concentration)
Q. Which of the following equations correct for Henderson-Hasselbach equation for weak acids?
✅ Correct Answer: (C)
PH = pKa + log (Ionized drug concentration/ Unionized drug concentration)
Q. If the pH of either side of the membrane is different, then the compartment whose pH favours greater ionization will have less amount of drug.
✅ Correct Answer: (B)
False