Q. In the equation, V dC/dt = dm/dt = A(Cs-Cb).√ γ D, what does γ stands for?
β
Correct Answer: (B)
Rate of surface renewal
Biopharmaceutics and Pharmacokinetic MCQs and Notes
Q. The maximum amount of solute dissolved in a given solvent under standard conditions of temperature, pressure, and pH is known as __________
β
Correct Answer: (D)
Absolute or intrinsic solubility
Q. Which are the two rate-determining step of drug absorption when given orally?
β
Correct Answer: (C)
Dissolution and permeation through the membrane
Q. In the equation, Wo1/3-W1/3=Kt, K stands for ____________
β
Correct Answer: (C)
Dissolution constant
Q. What does the interfacial barrier model states?
β
Correct Answer: (A)
An intermediate concentration exists at the interface
Q. Which model does not approve the existence of the stagnant layer in the solid-liquid interface?
β
Correct Answer: (D)
Danckwert’s model
Q. In the equation G=Ki (Cs-Cb), what does G stands for______________
β
Correct Answer: (A)
Dissolution rate per unit area
Q. Which theory takes into account that a thin film is created by the solution of the solid at the solidliquid interface?
β
Correct Answer: (B)
Diffusion layer model
Q. Which one of these is not a theory of Drug dissolution?
β
Correct Answer: (B)
Fick’s law of diffusion
Q. What should be the ideal solubility rate of an orally administered drug in the pH range of 2 to 8?
β
Correct Answer: (D)
1-2 mg/ml