Q. Which of the following is not a category of 2 compartment model?
✅ Correct Answer: (D)
Two compartment model with elimination from both the compartments
Biopharmaceutics and Pharmacokinetic MCQs and Notes
Q. Which organ comprises the peripheral compartment in a two compartment model?
✅ Correct Answer: (D)
Muscles
Q. Which organs comprise the central compartment in a two compartment model?
✅ Correct Answer: (D)
Liver
Q. What is the equation to find out hepatic clearance?
✅ Correct Answer: (B)
Rate of elimination by kidney/plasma drug concentration
Q. To have a plasma distribution value of 900 ml and plasma drug concentration to be 1.2 mg/ml what should be the amount of drug that should be given to the patient?
✅ Correct Answer: (C)
1080 mg
Q. The i.v. bolus dosage is 500mg and the plasma drug concentration is 0.8 mg/ml. What should be the volume of distribution?
✅ Correct Answer: (C)
625 ml
Q. What is the equation to find out the apparent volume of distribution?
✅ Correct Answer: (A)
Amount of drug in the body/plasma drug concentration
Q. What is meant by elimination half-life?
✅ Correct Answer: (D)
Time take for half of the amount of drug to get completely eliminated from the body as well as plasma
Q. In the equation log C = log Co – KEt/2.303, what does Co stand for _______
✅ Correct Answer: (D)
Plasma drug concentration immediately after i.v. injection.
Q. How much time does an intravenously administered drug take to complete a complete circulation?
✅ Correct Answer: (C)
1-3 min