πŸ“Š Biopharmaceutics and Pharmacokinetic
Q. Following intravenous administration, drugs are distributed fastest to:
  • (A) the skin, kidney, and brain
  • (B) the liver, kidney, and brain
  • (C) the liver, adipose, and brain
  • (D) the liver, kidney, and adipose
πŸ’¬ Discuss
βœ… Correct Answer: (B) the liver, kidney, and brain
πŸ“Š Biopharmaceutics and Pharmacokinetic
Q. Plasma Protein binding …………..the volume of distribution of drugs.
  • (A) increases
  • (B) decreases
  • (C) no change
  • (D) none of the above
πŸ’¬ Discuss
βœ… Correct Answer: (B) decreases
πŸ“Š Biopharmaceutics and Pharmacokinetic
Q. The volume of distribution (Vd) relates:
  • (A) Single to a daily dose of an administered drug
  • (B) An administered dose to a body weight
  • (C) An unchanged drug reaching the systemic circulation
  • (D) The amount of a drug in the body to the concentration of a drug in plasma
πŸ’¬ Discuss
βœ… Correct Answer: (D) The amount of a drug in the body to the concentration of a drug in plasma
πŸ“Š Biopharmaceutics and Pharmacokinetic
Q. The volume of distribution of drugs is:
  • (A) An expression of total body volume
  • (B) A measure of total fluid volume
  • (C) A relationship between the total amount of drug in the body and the concentration of the drug in the blood
  • (D) Proportional to bioavailability of the drug
πŸ’¬ Discuss
βœ… Correct Answer: (C) A relationship between the total amount of drug in the body and the concentration of the drug in the blood
πŸ“Š Biopharmaceutics and Pharmacokinetic
Q. The loading dose of a drug is based upon the
  • (A) time taken for complete elimination
  • (B) percentage of drug excreted unchanged in urine
  • (C) percentage of drug bound to plasma protein
  • (D) apparent volume of distribution and the desired drug concentration in plasma
πŸ’¬ Discuss
βœ… Correct Answer: (D) apparent volume of distribution and the desired drug concentration in plasma