Dosage Form Design MCQs and Notes

V

Vikash Gupta • 33.56K Points
Instructor I

Q 1. The constants that represent reversible transfer of drug between compartments are called as

(A) microconstants
(B) macroconstant
(C) Infusion
(D) Lag time

G

Gopal Sharma • 38.32K Points
Coach

Q 2. Select the formula to calculate elimination half life

(A) t1/2 = 0.693 + Ke
(B) t1/2 = 0.693 / Ke
(C) t1/2 = 0.693 × Ke
(D) t1/2 = 0.693 – Ke

P

Priyanka Tomar • 35.28K Points
Coach

Q 3. IV infusion model follows

(A) Zero order absorption and first order elimination kinetic
(B) No absorption and first order elimination kinetic
(C) No absorption and Zero order elimination kinetic
(D) First order absorption and first order elimination kinetic

R

Rakesh Kumar • 28.44K Points
Instructor II

Q 4. Select the formula to calculate steady state concentration follows IV infusion

(A) Css= Infusion Rate/ Clearance
(B) Css= Clearance / Infusion Rate
(C) Css= Infusion Rate X Clearance
(D) Css = Infusion Rate - Clearance

V

Vikash Gupta • 33.56K Points
Instructor I

Q 5. In compartment modeling the term "Open" indicates

(A) Unidirectional input and output
(B) All compartments are open
(C) Body is open
(D) None of the above

S

Shiva Ram • 30.44K Points
Instructor I

Q 6. The steady-state concentration of a drug can be double by:

(A) Doubling the both rate of infusion and concentration of drug.
(B) Doubling the rate of infusion only.
(C) Doubling the loading dose but maintaining the infusion rate.
(D) Tripling the rate of infusion.

P

Priyanka Tomar • 35.28K Points
Coach

Q 7. Under compartment modeling, Wegner-Nelson-Method involves

(A) Determination of absorption rate constant (Ka) from %ARA Vs time curve
(B) Determination of elimination rate constant (Ka) from % ARA Vs time curve
(C) Determination of absorption rate constant (Ke) from %ARA •Vs Concentration curve
(D) Determination of plasma half life

G

Gopal Sharma • 38.32K Points
Coach

Q 8. Under non compartment analysis the following formula is used for calculation

(A) MRT = AUMC / AUC
(B) AUMC = MRT / AUC
(C) MRT = AUC / AUMC
(D) AUC = AUMC / MRT

V

Vinay • 28.75K Points
Instructor II

Q 9. The area under serum concentration time curve of drug represents

(A) The biological half life of the drug
(B) Amount of drug biotransformed
(C) The amount of drug absorbed
(D) The amount of drug excreted in urine

R

Ranjeet • 34.60K Points
Instructor I

Q 10. T % (Half life time) of a drug can determine all of the following except

(A) Closing interval
(B) Therapeutic dose
(C) Elimination time
(D) Steady plasma concentration

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