πŸ“Š Dosage Form Design
Q. The constants that represent reversible transfer of drug between compartments are called as
  • (A) microconstants
  • (B) macroconstant
  • (C) Infusion
  • (D) Lag time
πŸ’¬ Discuss
βœ… Correct Answer: (A) microconstants
πŸ“Š Dosage Form Design
Q. Select the formula to calculate elimination half life
  • (A) t1/2 = 0.693 + Ke
  • (B) t1/2 = 0.693 / Ke
  • (C) t1/2 = 0.693 × Ke
  • (D) t1/2 = 0.693 – Ke
πŸ’¬ Discuss
βœ… Correct Answer: (B) t1/2 = 0.693 / Ke
πŸ“Š Dosage Form Design
Q. IV infusion model follows
  • (A) Zero order absorption and first order elimination kinetic
  • (B) No absorption and first order elimination kinetic
  • (C) No absorption and Zero order elimination kinetic
  • (D) First order absorption and first order elimination kinetic
πŸ’¬ Discuss
βœ… Correct Answer: (A) Zero order absorption and first order elimination kinetic
πŸ“Š Dosage Form Design
Q. Select the formula to calculate steady state concentration follows IV infusion
  • (A) Css= Infusion Rate/ Clearance
  • (B) Css= Clearance / Infusion Rate
  • (C) Css= Infusion Rate X Clearance
  • (D) Css = Infusion Rate - Clearance
πŸ’¬ Discuss
βœ… Correct Answer: (A) Css= Infusion Rate/ Clearance
πŸ“Š Dosage Form Design
Q. In compartment modeling the term "Open" indicates
  • (A) Unidirectional input and output
  • (B) All compartments are open
  • (C) Body is open
  • (D) None of the above
πŸ’¬ Discuss
βœ… Correct Answer: (A) Unidirectional input and output
πŸ“Š Dosage Form Design
Q. The steady-state concentration of a drug can be double by:
  • (A) Doubling the both rate of infusion and concentration of drug.
  • (B) Doubling the rate of infusion only.
  • (C) Doubling the loading dose but maintaining the infusion rate.
  • (D) Tripling the rate of infusion.
πŸ’¬ Discuss
βœ… Correct Answer: (B) Doubling the rate of infusion only.
πŸ“Š Dosage Form Design
Q. Under compartment modeling, Wegner-Nelson-Method involves
  • (A) Determination of absorption rate constant (Ka) from %ARA Vs time curve
  • (B) Determination of elimination rate constant (Ka) from % ARA Vs time curve
  • (C) Determination of absorption rate constant (Ke) from %ARA •Vs Concentration curve
  • (D) Determination of plasma half life
πŸ’¬ Discuss
βœ… Correct Answer: (A) Determination of absorption rate constant (Ka) from %ARA Vs time curve
πŸ“Š Dosage Form Design
Q. Under non compartment analysis the following formula is used for calculation
  • (A) MRT = AUMC / AUC
  • (B) AUMC = MRT / AUC
  • (C) MRT = AUC / AUMC
  • (D) AUC = AUMC / MRT
πŸ’¬ Discuss
βœ… Correct Answer: (A) MRT = AUMC / AUC
πŸ“Š Dosage Form Design
Q. The area under serum concentration time curve of drug represents
  • (A) The biological half life of the drug
  • (B) Amount of drug biotransformed
  • (C) The amount of drug absorbed
  • (D) The amount of drug excreted in urine
πŸ’¬ Discuss
βœ… Correct Answer: (D) The amount of drug excreted in urine
πŸ“Š Dosage Form Design
Q. T % (Half life time) of a drug can determine all of the following except
  • (A) Closing interval
  • (B) Therapeutic dose
  • (C) Elimination time
  • (D) Steady plasma concentration
πŸ’¬ Discuss
βœ… Correct Answer: (B) Therapeutic dose