πŸ“Š Biopharmaceutics and Pharmacokinetic
Q. Elimination is expressed as follows:
  • (A) Rate of renal tubular reabsorption
  • (B) Clearance speed of some volume of blood from substance
  • (C) Time required decreasing the amount of drug in plasma by one-half
  • (D) Clearance of an organism from a xenobiotic
πŸ’¬ Discuss
βœ… Correct Answer: (D) Clearance of an organism from a xenobiotic
πŸ“Š Biopharmaceutics and Pharmacokinetic
Q. For a drug that is eliminated primarily by renal glomerular filtration, the theoretical maximum clearance is approximately
  • (A) 1-2 milliliters/min
  • (B) 12 milliliters/min
  • (C) 120 milliliters/min
  • (D) 1200 milliliters/min
πŸ’¬ Discuss
βœ… Correct Answer: (C) 120 milliliters/min
πŸ“Š Biopharmaceutics and Pharmacokinetic
Q. Total body clearance is
  • (A) the drug elimination rate divided by the plasma drug concentration
  • (B) the drug elimination rate divided by the Vd
  • (C) the amount of drug in body divided by the plasma drug concentration
  • (D) None of the above
πŸ’¬ Discuss
βœ… Correct Answer: (A) the drug elimination rate divided by the plasma drug concentration
πŸ“Š Biopharmaceutics and Pharmacokinetic
Q. The renal clearance of inulin is used as a measurement of
  • (A) effective renal blood flow
  • (B) rate of renal drug excretion
  • (C) active renal secretion
  • (D) glomerular filtration rate
πŸ’¬ Discuss
βœ… Correct Answer: (D) glomerular filtration rate
πŸ“Š Biopharmaceutics and Pharmacokinetic
Q. Stimulation of liver microsomal enzymes can:
  • (A) Require the dose increase of some drugs
  • (B) Require the dose decrease of some drugs
  • (C) Prolong the duration of the action of a drug
  • (D) Intensify the unwanted reaction of a drug
πŸ’¬ Discuss
βœ… Correct Answer: (A) Require the dose increase of some drugs