Q. Tick the drug type for which microsomal oxidation is the most prominent:
✅ Correct Answer: (A)
Lipid soluble
Biopharmaceutics and Pharmacokinetic MCQs and Notes
Q. Conjugation is:
✅ Correct Answer: (C)
Coupling of a drug with an endogenous substrate
Q. Which of the following processes proceeds in the second phase of biotransformation?
✅ Correct Answer: (A)
Acetylation
Q. Metabolic transformation (phase 1) is:
✅ Correct Answer: (A)
Glucuronide formation
Q. Choose the drug type for which microsomal oxidation is the most prominent.
✅ Correct Answer: (B)
Lipid soluble
Q. Select the right statement.
✅ Correct Answer: (B)
Microsomal oxidation results in an increase of ionization and water solubility of a drug
Q. Biotransformation of the drugs is to render them:
✅ Correct Answer: (A)
Less lipid soluble
Q. Which one of the following is the correct order of the drugs binding to various plasma protein?
✅ Correct Answer: (C)
Albumin > alpha-1 acid glycoprotein > lipoproteins > globulins
Q. Binding of drugs falls into 2 components those are _______________
✅ Correct Answer: (A)
Binding of drugs to blood components and to extravascular tissue
Q. Which one of the following bonds is not generally a bond through which a drug will bind in our body?
✅ Correct Answer: (D)
Covalent bond