Q. The gold coating on a USP Dissolution apparatus - I basket should be:
✅ Correct Answer: (A)
Not more than 2.5 m in thickness
Biopharmaceutics and Pharmacokinetic MCQs and Notes
Q. In vitro dissolution rate studies on drug product are useful in bioavailability evaluation if they are correlated with
✅ Correct Answer: (D)
In vivo studies in human
Q. USP Apparatus 5 is
✅ Correct Answer: (B)
paddle over disk
Q. ………………is the ratio of the mean residence time to the absorption time
✅ Correct Answer: (A)
Absorption number
Q. According to Biopharmaceutics Classification System (BCS), Class II drugs have
✅ Correct Answer: (B)
Low solubility /High permeability
Q. Which of the following compounds are used as agents to determine Glomerular Filtration Rate?
✅ Correct Answer: (C)
Creatinine
Q. What is the driving force for glomerular filtration?
✅ Correct Answer: (D)
Hydrostatic pressure of blood flow
Q. Biotransformation of a medicinal substance results in:
✅ Correct Answer: (B)
Faster urinary excretion
Q. For the calculation of the volume of distribution (Vd) one take into account:
✅ Correct Answer: (B)
Concentration of substance in plasma
Q. The term "biotransformation" includes the following.
✅ Correct Answer: (B)
Process of physicochemical and biochemical alteration of a drug in the body