Q. What is interaction of phenobarbitone and warfarin?
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Correct Answer: (A)
Displacement of warfarin from binding site
Biopharmaceutics and Pharmacokinetic MCQs and Notes
Q. Which of the following drug bind to α1 globulin?
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Correct Answer: (A)
Steroids
Q. The value of association constant, Ka and the number of binding sites N can be obtained by
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Correct Answer: (D)
All of the above
Q. Which of the following is a correct method to find the fraction of unbound drug in plasma? Given where Cu is the concentration of unbound drug and C is total plasma drug concentration.
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Correct Answer: (C)
Cu/C
Q. Displacement interactions are significant in the case of drugs which are more than 95% bound.
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Correct Answer: (A)
True
Q. Penicillin has short plasma half-life although it can bind to plasma protein rigidly.
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Correct Answer: (A)
True
Q. Only unbound or free drug is capable of being eliminated.
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Correct Answer: (A)
True
Q. In the equation X= Vd C, what does X stands for?
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Correct Answer: (D)
Amount of drug in the body
Q. The extent of drug-protein binding can change with both changes in protein and drug concentration.
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Correct Answer: (A)
True
Q. Which drug easily bind to AAG?
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Correct Answer: (A)
Cationic drug