G Gopal Sharma π Tutor III β 38.32K Points π Biopharmaceutics and Pharmacokinetic Q. The area under the serum concentration time curve of the drug represents: (A) the biological half life of the drug (B) the amount of drug in the original dosage form (C) The amount of drug absorbed (D) The amount of drug excreted in the urine ποΈ Show Answer π¬ Discuss π Share β‘Menu β Correct Answer: (C) The amount of drug absorbed
A Admin π Coach β 38.23K Points π Biopharmaceutics and Pharmacokinetic Q. Biological Half life equation for first order process is (A) t1/2 = a/2K (B) t1/2 = 0.693/K (C) ) t1/2 = 1/aK (D) ) t1/2 = 3/2 K ποΈ Show Answer π¬ Discuss π Share β‘Menu β Correct Answer: (B) t1/2 = 0.693/K
R Ranjeet π Tutor III β 34.60K Points π Biopharmaceutics and Pharmacokinetic Q. Systemic clearance (Cl) is related with: (A) only the concentration of substances in plasma (B) only the elimination rate constant (C) volume of distribution, half life and elimination rate constant (D) bioavailability and half life ποΈ Show Answer π¬ Discuss π Share β‘Menu β Correct Answer: (C) volume of distribution, half life and elimination rate constant
S Shiva Ram π Master β 30.44K Points π Biopharmaceutics and Pharmacokinetic Q. Elimination rate constant (Kelim) is defined by the following parameter: (A) rate of absorption (B) maximal concentration of a substance in plasma (C) highest single dose (D) half life (t1/2) ποΈ Show Answer π¬ Discuss π Share β‘Menu β Correct Answer: (D) half life (t1/2)
G Gopal Sharma π Tutor III β 38.32K Points π Biopharmaceutics and Pharmacokinetic Q. Half life (t1/2) does not depend on: (A) biotransformation (B) time of drug absorption (C) concentration of a drug in plasma (D) rate of drug elimination ποΈ Show Answer π¬ Discuss π Share β‘Menu β Correct Answer: (B) time of drug absorption
R Ram Sharma π Coach β 193.88K Points π Biopharmaceutics and Pharmacokinetic Q. Half life (t1/2) is the time required to: (A) change the amount of a drug in plasma by half during elimination (B) metabolize a half of an introduced drug into the active metabolite (C) absorb a half of an introduced drug (D) bind a half of an introduced drug to plasma proteins ποΈ Show Answer π¬ Discuss π Share β‘Menu β Correct Answer: (A) change the amount of a drug in plasma by half during elimination
R Rakesh Kumar π Hard Worker β 28.44K Points π Biopharmaceutics and Pharmacokinetic Q. The half life of a drug eliminated by first order elimination kinetics will be longer in individuals who have an: (A) increased volume of distribution or increased clearance (B) increased volume of distribution or decreased clearance (C) decreased volume of distribution or increased clearance (D) decreased volume of distribution or decreased clearance ποΈ Show Answer π¬ Discuss π Share β‘Menu β Correct Answer: (B) increased volume of distribution or decreased clearance
R Ranjeet π Tutor III β 34.60K Points π Biopharmaceutics and Pharmacokinetic Q. The biological half-life of drug: (A) is a constant physical property of the drug (B) is a constant chemical property of the drug (C) may be increased in patients with impaired renal failure (D) may be decreased in patients by giving the drug by rapid I.V. injection ποΈ Show Answer π¬ Discuss π Share β‘Menu β Correct Answer: (C) may be increased in patients with impaired renal failure
G Gopal Sharma π Tutor III β 38.32K Points π Biopharmaceutics and Pharmacokinetic Q. The multicompartment models are intended to provide……………. (A) Therapeutic activity of the drug (B) Achieve maximum efficacy (C) Both of the above (D) None of the above ποΈ Show Answer π¬ Discuss π Share β‘Menu β Correct Answer: (C) Both of the above
G Gopal Sharma π Tutor III β 38.32K Points π Biopharmaceutics and Pharmacokinetic Q. A multicompartment model assumes that all transfer rate processes for the passage of drug into or out of individual compartments are…………….. processes. (A) First-order (B) Second order (C) Pseudo order (D) None of the above ποΈ Show Answer π¬ Discuss π Share β‘Menu β Correct Answer: (A) First-order