Q. What is the mechanism of drug excretion for skin excretion?
✅ Correct Answer: (C)
Passive diffusion
Biopharmaceutics and Pharmacokinetic MCQs and Notes
Q. What is the pH of the milk secreted by human mothers?
✅ Correct Answer: (A)
6.4-7.6
Q. Which compounds are excreted through the lungs?
✅ Correct Answer: (B)
Gaseous
Q. For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance?
✅ Correct Answer: (B)
1.75 ml/mm
Q. What is the equation for biliary clearance?
✅ Correct Answer: (B)
Biliary excretion rate/ plasma drug concentration
Q. What is the molecular weight cut off for biliary excretion?
✅ Correct Answer: (B)
More than 300 Dalton
Q. Compounds excreted in bile is classified into 3 categories. Which one of the following does not come under the categories?
✅ Correct Answer: (D)
Drugs with bile/plasma concentration ratio above 1000
Q. Which one of the following is the principal organ for drug excretion?
✅ Correct Answer: (C)
Kidneys
Q. What will be the rate of filtration if the rate of secretion is 0.9 ml/ sec, rate of reabsorption is 0.2 ml/sec and the rate of excretion is 2ml/sec for a particular drug?
✅ Correct Answer: (D)
1.3ml/sec
Q. How do you calculate the rate of excretion by kidneys?
✅ Correct Answer: (B)
Rate of filtration + rate of secretion – Rate of absorption