Pharmaceutical Technology 2 MCQs and Notes

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📊 Pharmaceutical Technology 2
Q. Durability of a tablet to combined effects of shock and abrasion is evaluated by using.
  • (A) Hardness tester
  • (B) Disintegration test apparatus
  • (C) Friabilator
  • (D) Screw gauge
💬 Discuss
✅ Correct Answer: (C) Friabilator

Explanation:

A friabilator is used to evaluate the durability of tablets by subjecting them to mechanical shock and abrasion, simulating the stress they may experience during handling, packaging, and transportation. It helps determine the tablet’s friability, i.e., its tendency to crumble.

📊 Pharmaceutical Technology 2
Q. Unless otherwise stated in the individual monograph of the pharmacopoeia, in the disintegration test for enteric coated tablets, first the dissolution is carried out in.
  • (A) 0.1N HCl
  • (B) Phosphate buffer
  • (C) water
  • (D) 0.1 M H2SO4
💬 Discuss
✅ Correct Answer: (C) water
📊 Pharmaceutical Technology 2
Q. A retardant material that forms a hydrophilic matrix in the formulation of matrix tablets is.
  • (A) HPMC
  • (B) CAP
  • (C) Polyethylene
  • (D) Carnauba wax
💬 Discuss
✅ Correct Answer: (A) HPMC
📊 Pharmaceutical Technology 2
Q. One of the following is used as a pH dependent controlled release excipient.
  • (A) Carnauba wax
  • (B) HPMC Phthalate
  • (C) Methyl cellulose
  • (D) Glyceryl Monostearate
💬 Discuss
✅ Correct Answer: (B) HPMC Phthalate
📊 Pharmaceutical Technology 2
Q. A water soluble substance used as coating material in microencapsulation process is:
  • (A) Polyethylene
  • (B) Silicone
  • (C) HEC
  • (D) Paraffin
💬 Discuss
✅ Correct Answer: (C) HEC
📊 Pharmaceutical Technology 2
Q. Which of the following industrial dryer is used to dry tablet granules?
  • (A) Drum Dryer
  • (B) Fluid dryer
  • (C) Spray dryer
  • (D) Freeze Dryer
💬 Discuss
✅ Correct Answer: (B) Fluid dryer
📊 Pharmaceutical Technology 2
Q. Which filler can NOT be used for the preparation of tablets for amine containing basic drugs to avoid discoloration of the tablets?
  • (A) Dicalcium Phosphate
  • (B) Microcrystalline cellulose
  • (C) Starch
  • (D) Lactose
💬 Discuss
✅ Correct Answer: (D) Lactose
📊 Pharmaceutical Technology 2
Q. What is Primogel?
  • (A) Substituted HPMC for direct compression
  • (B) Modified MCC for direct compression
  • (C) Hydrogelling polymer for gel formation
  • (D) Modified starch for disintegration
💬 Discuss
✅ Correct Answer: (D) Modified starch for disintegration
📊 Pharmaceutical Technology 2
Q. According to USP, the speed regulating device of the dissolution apparatus should be capable of maintaining the speed within limits of what % of the selected speed?
  • (A) 1%
  • (B) 2%
  • (C) 4%
  • (D) 5%
💬 Discuss
✅ Correct Answer: (C) 4%
📊 Pharmaceutical Technology 2
Q. Larger values of Ky in the Heckel Plot indicate formation of what quality of tablets?
  • (A) Harder tablets
  • (B) Soft tablets
  • (C) Brittle tablets
  • (D) Fluffy tablets
💬 Discuss
✅ Correct Answer: (A) Harder tablets

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