Q. Trapping of iodide by the following organ/organs is enhanced by thyrotropin:
β
Correct Answer: (A)
Thyroid
Pharmaceutical Chemistry - Medicinal Chemistry 4 MCQs and Notes
Q. Plasma expanders are used in the following conditions except: (Note: They will increase circulating blood volume and thus preload on heart, which will worsen heart failure.)
β
Correct Answer: (A)
Congestive heart failure
Q. Select the hypolipidemic drug that enhances lipoprotein synthesis, fatty acid oxidation and LDLreceptor expression in liver through paroxisome proliferator-activated receptor α
β
Correct Answer: (C)
Bezafibrate
Q. Select the most appropriate hypolipidemic drug for a patient with raised LDL-cholesterol level but normal triglyceride level:
β
Correct Answer: (A)
A HMG-CoA reductase inhibitor
Q. Choose the most potent and most efficacious LDL cholesterol lowering HMG-CoA reductase inhibitor:
β
Correct Answer: (D)
Atorvastatin
Q. The following is true of clopidogrel except:
β
Correct Answer: (A)
It is a GPIIb/IIIa receptor antagonist
Q. Aspirin prolongs bleeding time by inhibiting the synthesis of:
β
Correct Answer: (D)
Thromboxane A2 in platelets
Q. The most important complication of streptokinase therapy is:
β
Correct Answer: (B)
Bleeding
Q. Which fibrinolytic agent(s) selectively activate(s) fibrin bound plasminogen rather than circulating plasminogen:
β
Correct Answer: (C)
Alteplase
Q. Choose the drug of which IUPAC name is 1,1-dimethylbiguanide.
β
Correct Answer: (B)
Metformin